Safely delete $NtUninstall folders

How To: Remove $NtUninstall folders
www.tech-pro.net/how-to-remove-ntuninstall-folders.html

The one thing to keep in mind is that there are Registry entries and a
few misc. files that are tied to each hotfix/update. Deleting the
$NTUninstallKB folders will leave these associated entries/files as
orphans. Therefore you might consider a tool designed specifically to
handle this task
(http://forum.brain-cluster.com/index.php/t/107918/)

ISSUE: Still can't find a way to remove multiple uninstall folders at once
May 5, 2011 UPDATE:
Commercial tool available: "Update Cleanup" (www.pc-shareware.com/update.htm)

Tool to periodically and automatically remove Windows Update backup files:
DiskMax - www.koshyjohn.com/software/diskmax/
Q: Will DiskMax remove associated entry on Add/Remove applet on Control Panel?
A: The entries are not removed because I cannot be sure if any applications use them to determine whether an update is installed or not.